Kevin Doyle's 10th international goal set Ireland on the road to a comfortable victory in Andorra as Giovanni Trapattoni's men completed the first half of their European mission.
Doyle's seventh-minute strike gave Ireland an advantage they never threatened to surrender and when defender Ildefons Lima deflected Aiden McGeady's shot into his own net 13 minutes later, the points were effectively safe.
Russia's victory in Slovakia means they will win Group B if they beat the Andorrans at home on Tuesday evening, but a draw with Armenia will be enough to send the Republic into the Euro 2012 play-offs.
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